KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS8L2
All Species:
3.94
Human Site:
S479
Identified Species:
12.38
UniProt:
Q9H6S3
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6S3
NP_073609.2
715
80621
S479
G
D
A
L
P
P
V
S
S
P
H
T
H
R
G
Chimpanzee
Pan troglodytes
XP_512904
745
82543
E510
P
E
S
E
P
Q
L
E
S
E
T
A
G
K
W
Rhesus Macaque
Macaca mulatta
XP_001116697
615
68955
D408
L
L
S
R
D
A
V
D
F
L
R
G
H
L
V
Dog
Lupus familis
XP_534881
791
88639
N487
V
A
F
K
P
T
P
N
R
H
M
D
R
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q99K30
729
82211
S482
E
D
I
A
P
P
G
S
S
P
H
A
N
R
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510664
556
62861
S349
E
E
A
A
V
W
E
S
L
G
Q
A
W
S
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666818
677
76506
A467
S
P
A
P
R
K
Y
A
K
I
R
Y
H
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785396
970
107261
P715
G
S
A
M
P
T
P
P
P
P
A
P
K
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.2
79.7
42.5
N.A.
84
N.A.
N.A.
29
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
N.A.
24.6
Protein Similarity:
100
58.2
80.8
60.1
N.A.
90.1
N.A.
N.A.
46.1
N.A.
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
40.5
P-Site Identity:
100
13.3
13.3
6.6
N.A.
60
N.A.
N.A.
13.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
40
20
13.3
N.A.
66.6
N.A.
N.A.
20
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
50
25
0
13
0
13
0
0
13
38
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
0
13
0
0
13
0
0
0
13
0
0
0
% D
% Glu:
25
25
0
13
0
0
13
13
0
13
0
0
0
0
0
% E
% Phe:
0
0
13
0
0
0
0
0
13
0
0
0
0
13
0
% F
% Gly:
25
0
0
0
0
0
13
0
0
13
0
13
13
0
25
% G
% His:
0
0
0
0
0
0
0
0
0
13
25
0
38
0
0
% H
% Ile:
0
0
13
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
13
0
13
0
0
13
0
0
0
13
13
0
% K
% Leu:
13
13
0
13
0
0
13
0
13
13
0
0
0
13
0
% L
% Met:
0
0
0
13
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
0
0
13
13
0
% N
% Pro:
13
13
0
13
63
25
25
13
13
38
0
13
0
13
0
% P
% Gln:
0
0
0
0
0
13
0
0
0
0
13
0
0
0
0
% Q
% Arg:
0
0
0
13
13
0
0
0
13
0
25
0
13
25
0
% R
% Ser:
13
13
25
0
0
0
0
38
38
0
0
0
0
13
0
% S
% Thr:
0
0
0
0
0
25
0
0
0
0
13
13
0
0
13
% T
% Val:
13
0
0
0
13
0
25
0
0
0
0
0
0
0
38
% V
% Trp:
0
0
0
0
0
13
0
0
0
0
0
0
13
0
13
% W
% Tyr:
0
0
0
0
0
0
13
0
0
0
0
13
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _